Infection Prevention & Wound Care

Clean and dress wounds without a medical kit, recognise infection progression to sepsis, irrigate correctly, use improvised antiseptics, and know when infection has become life-threatening.

infectionwound-carecleaningdressingantibioticssepsis

A wound that is well-managed in the first few hours is dramatically less likely to become infected than one left to chance. In a disaster or resource-limited setting, where access to antibiotics and professional wound care may be delayed by days, the difference between a wound that heals and one that becomes life-threatening often comes down to the quality of initial cleaning and dressing.

Sepsis — the body's overwhelming systemic response to infection — kills approximately 11 million people worldwide annually. In a disaster context, wounds that become infected and progress to sepsis without early recognition are a major cause of preventable death. This guide covers the mechanics of correct wound cleaning, wound assessment, dressing technique, and the signs that infection has progressed beyond local tissue to systemic threat.

Assessing the Wound

Before cleaning, assess:

Type of Wound

Wound TypeInfection RiskNotes
Clean laceration (e.g., knife cut)ModerateRelatively low contamination
Dirty laceration (debris in wound)HighAggressive cleaning essential
Puncture woundHighNarrow entry, deep penetration; hard to clean; high anaerobic risk (tetanus)
Animal or human biteVery highExtensive bacterial contamination; consider rabies risk
Avulsion (tissue torn away)HighIrregular edges, contaminated
Crush injuryVery highDamaged tissue is poor environment for healing; ideal for infection
Wound with foreign body (gravel, glass)Very highMust remove foreign body or infection is certain

Wound Severity and Referral Criteria

Even without a medical kit, certain wounds need professional attention as soon as available:

  • Wounds that have penetrated a joint cavity
  • Wounds with suspected tendon, nerve, or vascular involvement
  • Contaminated wounds that cannot be adequately cleaned
  • Wounds to the face near the eye
  • Any bite wound (animal or human)
  • Wounds in people who are immunocompromised, diabetic, or on steroids
  • Wounds where tetanus immunisation is not current (last booster within 10 years for clean wounds; 5 years for dirty wounds)

Wound Irrigation — The Most Important Step

High-pressure wound irrigation removes bacteria, debris, and devitalised tissue more effectively than any antiseptic. This is the single most important step in infection prevention.

Technique

  1. Prepare the irrigating fluid — clean water is the most accessible and is effective. Ideal options in order:

    • Sterile saline (0.9% sodium chloride in sterile water)
    • Clean potable water
    • Boiled water, cooled
    • Tap water (most studies show equivalent infection rates to sterile saline for wound irrigation)
  2. Create irrigation pressure — a 35–60 ml syringe with a 19-gauge needle produces the ideal pressure. Improvised equivalents:

    • A plastic bag with a small pin-hole
    • A water bottle with a pin-hole in the cap
    • Pouring from a cup from height creates some pressure
  3. Irrigate directly into the wound — aim the stream into the wound cavity, not just onto the surface

  4. Volume — use significant volumes: at minimum 50–100 ml per cm of wound length; for heavily contaminated wounds, 200–500 ml total. More is better.

  5. Duration — irrigate until all visible debris is removed and the wound looks clean

⚠️ Do not inject irrigating fluid into a sealed puncture wound under high pressure — this can drive bacteria deeper into tissue planes. For puncture wounds, gentle irrigation at the opening is appropriate.

Removing Embedded Foreign Bodies

Visible debris, gravel, and glass should be removed with clean tweezers or clean fingers before dressing. Missed foreign bodies are a leading cause of wound infection failure.

If a foreign body cannot be removed (too deep, too fragile), document its presence and ensure professional care is sought.

Antiseptics — What to Use and What to Avoid

Antiseptics are useful for surface decontamination but are not a substitute for mechanical irrigation.

AntisepticAppropriate UseNotes
Povidone-iodine 10% (Betadine)Wound surface and skin around woundDilute 10x with water (1%) for wound irrigation — full-strength is tissue-toxic
Chlorhexidine 0.05%Wound and skin cleaningAvoid in ear canals, eye contact
Isopropyl alcohol (70%)Skin preparation onlyToxic to healing tissue in open wounds; do not pour into wounds
Hydrogen peroxide (3%)Limited; can loosen dried blood and debrisToxic to granulation tissue; destroys healing cells; avoid in healing wounds
Honey (raw, unpasteurised — manuka type)Wound dressing for infected woundsAntimicrobial properties; evidence base for use on chronic infected wounds

Alcohol (spirits — whisky, vodka): Useful for skin around the wound as a disinfectant. Painful and damaging to open wound tissue — do not pour into wounds.

Wound Dressing

After irrigation, cover the wound:

Dressing Options

  1. Non-adherent dressing — the ideal primary layer; does not stick to healing tissue; will not disrupt the wound on removal
  2. Clean gauze pad — pad over the primary layer to absorb discharge
  3. Bandage to hold in place — not too tight; allow some drainage

Improvised options when no medical dressings are available:

  • Clean cotton fabric cut from unused clothing; the inner layer of a folded material
  • Cling film as a non-adherent primary layer (acceptable for short periods)
  • A clean plastic bag over a hand wound

⚠️ Never apply adhesive dressings or tape directly to a wound surface — these pull healing tissue off when removed. Use a clean pad as the primary layer and tape the edges of the dressing to intact skin.

Dressing Changes

Change the dressing every 24–48 hours, or when it becomes saturated or soiled. Before each change:

  • Inspect for signs of infection (see below)
  • Irrigate again if debris is present
  • Do not disturb healthy granulating (pink, beaded) tissue — this is the healing base

Recognising Wound Infection

Local Infection (Cellulitis)

Signs appear 24–72 hours after injury or can develop in existing wounds:

  • Redness expanding beyond the wound edges — draw a line around the redness with a pen to monitor spread
  • Warmth of the surrounding skin
  • Swelling increasing
  • Pain increasing (a wound that was improving then becomes more painful)
  • Purulent discharge — yellow, green, or cloudy fluid from the wound
  • Wound breakdown — edges that were healing begin to separate

Treatment: If antibiotics are available and indicated by a healthcare provider, start them. Continue wound cleaning and dressing. Immobilise and elevate the affected limb. Monitor closely for systemic spread.

Signs of Spreading Infection — Escalate Urgently

These signs indicate the infection is extending beyond local tissue:

  • Red streaking extending from the wound along lymphatic channels toward the torso — a medical emergency
  • Swollen, tender lymph nodes near the wound
  • Systemic symptoms developing (see sepsis below)

Sepsis — Life-Threatening Systemic Infection

Sepsis is the body's dysregulated systemic response to infection. It can develop from a wound infection when bacteria or their toxins enter the bloodstream.

Suspect sepsis when a wound infection is accompanied by two or more of:

SignDetail
FeverTemperature above 38°C (100.4°F)
HypothermiaTemperature below 36°C (96.8°F)
Rapid heart rateOver 90 beats per minute
Rapid breathingOver 20 breaths per minute
ConfusionNew confusion or altered consciousness
Extreme weaknessSudden severe weakness out of proportion

⚠️ Sepsis is a medical emergency. A person who has a wound infection and is developing confusion, rapid breathing, or extreme weakness needs emergency hospital care immediately. Septic shock (sepsis with falling blood pressure) has a mortality of 30–50% even with intensive hospital care.

Field response for suspected sepsis:

  • Emergency services immediately
  • Lay the person down; fluids if available
  • Antibiotics if prescribed and available — start immediately; do not wait for confirmation

Tetanus Consideration

Tetanus (caused by Clostridium tetani) is a wound infection risk for dirty, deep, or puncture wounds in people whose tetanus immunisation is not current. In a post-disaster setting with no immediate medical access, a tetanus-prone wound in an unvaccinated person is a serious risk.

In the field: thorough irrigation reduces (but does not eliminate) risk. Medical evaluation and tetanus prophylaxis (vaccine + immunoglobulin) should be sought at the earliest opportunity for:

  • Deep or dirty wounds
  • Puncture wounds
  • Bite wounds
  • Wounds in anyone not immunised within 5–10 years

Quick Reference

StepAction
Wound assessmentType, contamination, severity, foreign bodies
IrrigationHigh pressure; clean water; 50–100 ml/cm wound length
AntisepticDilute povidone-iodine or chlorhexidine; not alcohol directly in wound
DressingNon-adherent layer; clean pad; secure with tape to intact skin
Dressing changeEvery 24–48 hours; inspect for infection
Local infection signsExpanding redness; warmth; increasing pain; pus
Spreading infectionRed streaking; swollen nodes — urgently seek care
Sepsis signsFever/hypothermia + rapid pulse + rapid breathing + confusion
Tetanus-prone woundSeek vaccination/immunoglobulin at earliest opportunity

This guide provides general wound care information for resource-limited or emergency situations. Wound infections and sepsis are medical emergencies requiring hospital-level care. Always seek professional wound assessment as soon as it becomes accessible.

// Sources

  • articleWHO Wound Infection Management Guidelines
  • articleCDC Wound Care and Infection Prevention
  • articleTCCC Wound Management
  • articleWilderness Medical Society Wound Care Guidelines
  • articleBMJ Wound Infection Diagnosis and Treatment
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